A beautiful and expensive hotel is The Imperator.
The FUAJ youth hostel (http://www.fuaj.fr/Nimes) has very friendly and informative local staff.
The Holiday Inn (http://www.holidayinn-nim...), Mercure (http://www.mercure.com), Ibis (http://www.ibishotel.com), Kyriad (http://www.hotel-kyriad-n...), Nimotel (http://www.inter-hotel.fr), Balladins (http://www.balladins.com) and the Hotel Formule 1 (http://www.hotelformule1.com) are all located in the retail park Parc Hotelier Ville Active, about 30 minutes' walk from the town centre and over the main road from Carrefour hypermarket.